Long-term treatment of poisoning with radioactive metals (americium, plutonium, curium, californium, berkelium).Ca-dtpa and zn-dtpaindicated for treatment of known or suspected internal contamination with plutonium, americium or curiumincreases elimination to decrease radiation exposure.ca-dtpa or zn-dtpa should be taken as soon as possible after internal contaminationremoval of individual from the radioactive sourceexternal decontaminationeffectiveness decreases when treatment is delayed, but ca-dtpa or zn-dtpa should be given as soon as the products are available.